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Article

Genomic insights into extrapulmonary tuberculosis reveal enrichment of lineage 2 with high drug resistance in specific clinical phenotypes

2025-08-06

Abstract excerpt

<h4>Background</h4> Certain M. tuberculosis lineages may preferentially infect extrapulmonary sites, potentially influencing clinical outcomes. Poor drug penetration at these sites may cause treatment failure, even in the absence of resistance. Timely access to resistance profiles and lineage information may support more effective, personalized treatment for extrapulmonary tuberculosis (EPTB). <h4>Methods</h4> W...

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Literature Corpus work
1753e87e-9710-55a5-8ebe-9f7e0b079122
DOI
10.1101/2025.08.05.25332932
Open publication

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Genomic insights into extrapulmonary tuberculosis reveal enrichment of lineage 2 with high drug resistance in specific clinical phenotypesDOI 10.1101/2025.08.05.25332932
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