Article
Transcriptomic Response of Brain Tissue to Focused Ultrasound-Mediated Blood-Brain Barrier Disruption Depends Strongly on Anesthesia
2020-07-26
Abstract excerpt
Focused ultrasound (FUS) mediated blood brain barrier disruption (BBBD) is a promising strategy for the targeted delivery of systemically-administered therapeutics to the central nervous system (CNS). Pre-clinical investigations of BBBD have been performed on different anesthetic backgrounds; however, the potential influence of the choice of anesthetic on the molecular response to BBBD is unknown, despite its pote...
Topics
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- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Neuroscience and Neuropharmacology Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Vascular Malformations Diagnosis and Treatment
Identifiers and source
- Literature Corpus work
- 17366f09-1abb-5d7a-bfad-48526c4bb08e
- DOI
- 10.1101/2020.07.24.211136
