Article

Data-driven development of an oral lipid-based nanoparticle formulation of a hydrophobic drug

2023-09-19

Abstract excerpt

Due to its cost-effectiveness, convenience, and high patient adherence, oral drug administration often remains the preferred approach. Yet, the effective delivery of hydrophobic drugs via the oral route is often hindered by their limited water solubility and first-pass metabolism. To mitigate these challenges, advanced delivery systems such as solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLC...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 16f02a13-0e02-5c6a-a2a8-743680e9589b
DOI: 10.21203/rs.3.rs-3329076/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Data-driven development of an oral lipid-based nanoparticle formulation of a hydrophobic drugDOI 10.21203/rs.3.rs-3329076/v1Read

Computationally guided high-throughput design of self-assembling drug nanoparticlesSemantic proximity Read

Unified Approaches in Modern Drug Delivery Covering Lipid Based Nanocarriers Controlled Release Mechanisms and Innovative Tablet TechnologiesSemantic proximity Read

Machine Learning-Driven Discovery of a Lipid Nanoparticle for In-Vivo T-Cell Transfection in Non-Human PrimatesSemantic proximity Read

Emerging Horizons in Lipid Based Drug Delivery Systems and Nanocarrier TherapeuticsSemantic proximity Read

Liposomal Formulations in Clinical Use Progress Challenges and Future DirectionsSemantic proximity Read

Rapid Carrier-Free Self-Assembled Aqueous Nanoformulations of Ten BCS Class II Drugs, Propofol, and Hydroxyapatite Using FAST NanoplatformSemantic proximity Read

Enhancing Therapeutic Outcomes with Smart Drug CarriersSemantic proximity Read

Integration of Liposomal Carriers, Nanoparticles, Oral Dosage Technologies, and Controlled Release Formulations in Modern Drug DeliverySemantic proximity Read

Biopharmaceutical Classification System (BCS)Semantic proximity Read

Advancements in Drug Delivery Systems from Chewable Tablets to NanomedicineSemantic proximity Read

Comparative Analysis of Liposomal and Surfactant-Based Drug Delivery SystemsSemantic proximity Read

Artificial Intelligence-Augmented Analytical Method Development and Validation in Pharmaceutical Manufacturing: Current Applications, Regulatory Landscape, and Future DirectionsSemantic proximity Read