Article

Assessment of Platelet Aggregation and Thrombin Generation in Patients with Familial Chylomicronemia Syndrome Treated with Volanesorsen: A Cross-Sectional Study

2024-07-08

Abstract excerpt

<h4>Background: </h4> The antisense oligonucleotide against APOC3 mRNA volanesorsen was recently introduced to treat Familial Chylomicronemia Syndrome (FCS). Cases of decreased platelet count are reported among patients treated with volanesorsen. The aim of the study is to evaluate platelet function and thrombin generation (TG) assessment in FCS patients receiving volanesorsen. We performed a cross-sectional study...

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Literature Corpus work: 16e6655e-77b7-523c-a2a8-e706d8f58d4a
DOI: 10.20944/preprints202407.0557.v1

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