Back to search

Article

Chiropteran (<em>Hypsugo savii</em>) Post-Natal Brain 2D-In Vitro Models: Primary Cell Isolation, Immortalization and Transcriptomic Changes

2026-06-09

Abstract excerpt

Bats are important reservoirs of zoonotic pathogens and valuable models for studying antiviral tolerance and neuroinflammation within a One Health framework. However, chiropteran neural 2D-in vitro models remain limited. Here, we established and characterized the first chiropteran primary (CpBCs) and immortalized (CiBCs) cell lines from Hypsugo savii species. To overcome the limited lifespan of CpBCs, immor-taliza...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
16202621-80cf-5e35-ad35-7a0caba10b52
DOI
10.20944/preprints202606.0723.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Chiropteran (<em>Hypsugo savii</em>) Post-Natal Brain 2D-In Vitro Models: Primary Cell Isolation, Immortalization and Transcriptomic ChangesDOI 10.20944/preprints202606.0723.v1
Generating bat primary and immortalised cell-lines from wing biopsiesSemantic proximity
Viral susceptibility and innate immune competency of <i>Carollia perspicillata</i> bat cells produced for virological studiesSemantic proximity
Establishing Primary and Stable Cell Lines from Frozen Wing Biopsies for Cellular, Physiological, and Genetic Studies in BatsSemantic proximity
Reprogrammed <i>Pteropus</i> Bat Stem Cells Present Distinct Immune Signature and are Highly Permissive for HenipavirusesSemantic proximity
Establishment, Immortalisation and Characterisation of Pteropid Bat Cell LinesSemantic proximity
Antiviral and Neuroprotective Abilities of Influenza Virus Infection in Tractable Brain OrganoidsSemantic proximity
Fishing Cat Cell Biobanking for ConservationSemantic proximity
Single-cell transcriptional atlas of the Chinese horseshoe bat ( <i>Rhinolophus sinicus</i> ) provides insight into the cellular mechanisms which enable bats to be viral reservoirsSemantic proximity
Reconstructing bat antiviral immunity using epithelial organoidsSemantic proximity
Human stem cell models to study host–virus interactions in the central nervous systemSemantic proximity
Development of two cell lines from Epinephelus coioides brain tissue for characterization of betanodavirus and megalocytivirus infectivity and propagationSemantic proximity
Bat pluripotent stem cells reveal unique entanglement between host and virusesSemantic proximity
Select a neighboring publication to make it the new centre.