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Human Cytomegalovirus modifies placental small extracellular vesicle secretion and composition towards a proviral phenotype to enhance infection of fetal recipient cells

2021-11-19

Abstract excerpt

Although placental small extracellular vesicles (sEVs) are extensively studied in the context of pregnancy, little is known about their role during human cytomegalovirus (hCMV) congenital infection, especially at the beginning of pregnancy. In this study, we examined the consequences of hCMV infection on sEVs production, composition and function using an immortalized human cytotrophoblast cell line derived from fi...

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Literature Corpus work
161f858c-9ee6-52f8-81b8-57ba509d890f
DOI
10.1101/2021.11.18.468660
Open publication

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Human Cytomegalovirus modifies placental small extracellular vesicle secretion and composition towards a proviral phenotype to enhance infection of fetal recipient cellsDOI 10.1101/2021.11.18.468660
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