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Article

Sterilizing immunity against SARS-CoV-2 in hamsters conferred by a novel recombinant subunit vaccine

2020-12-20

Abstract excerpt

A safe and effective SARS-CoV-2 vaccine is essential to avert the on-going COVID-19 pandemic. Here, we developed a subunit vaccine, which is comprised of CHO-expressed spike ectodomain protein (StriFK) and nitrogen bisphosphonates-modified zinc-aluminum hybrid adjuvant (FH002C). This vaccine candidate rapidly elicited the robust humoral response, Th1/Th2 balanced helper CD4 T cell and CD8 T cell immune response in...

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Identifiers and source

Literature Corpus work
160641cb-d2d9-563b-9bcb-1d75fb2af8dd
DOI
10.1101/2020.12.18.423552
Open publication

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Sterilizing immunity against SARS-CoV-2 in hamsters conferred by a novel recombinant subunit vaccineDOI 10.1101/2020.12.18.423552
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