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Cas3 of type I-Fa CRISPR-Cas system upregulates bacterial biofilm formation and virulence in Acinetobacter baumannii by affecting cilia-related and ompA genes expression

2024-08-20

Abstract excerpt

<title>Abstract</title> <p><italic>Acinetobacter baumannii</italic> (<italic>A.baumannii</italic>) is an important pathogen causing various nosocomial infections. CRISPR-Cas system is the adaptive immune system of bacteria, which is also closely related to the drug resistance and virulence of bacteria. In this study, we successfully constructed a <italic>cas3</italic> deletion mutant (19606Δ<italic>cas3</italic>)...

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Literature Corpus work
15d08aac-ee99-5757-9ae0-3682233b2bdd
DOI
10.21203/rs.3.rs-4658723/v1
Open publication

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Cas3 of type I-Fa CRISPR-Cas system upregulates bacterial biofilm formation and virulence in Acinetobacter baumannii by affecting cilia-related and ompA genes expressionDOI 10.21203/rs.3.rs-4658723/v1
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