Article
A self-amplifying RNA vaccine against COVID-19 with long-term room-temperature stability
2 Nov 2022
Abstract excerpt
mRNA vaccines were the first to be authorized for use against SARS-CoV-2 and have since demonstrated high efficacy against serious illness and death. However, limitations in these vaccines have been recognized due to their requirement for cold storage, short durability of protection, and lack of access in low-resource regions. We have developed an easily-manufactured, potent self-amplifying RNA (saRNA) vaccine...
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