Article

Elevated Expression of <i>MALAT1</i> Contributes to the Survival of Drug-Tolerant Persister Cells Following Targeted Therapy in Lung Adenocarcinoma

2026-05-12

Abstract excerpt

Lung adenocarcinomas frequently harbour actionable oncogenic mutations that are vulnerable to treatment with targeted therapies. While responses to targeted therapies are often initially dramatic, relapse is almost inevitable and prevents durable responses in advanced-stage patients. Relapse is, in part, caused by drug tolerant persister cells (DTPs) which are able to survive treatment by entering a reversible, do...

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Literature Corpus work: 1584e783-7543-59f9-9f78-9392e89ab92b
DOI: 10.64898/2026.05.07.723110

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