Article

Assessing Precision Antisense Oligonucleotide Therapy Eligibility for Infantile Genetic Epilepsies

2025-12-04

Abstract excerpt

<h4>Importance</h4> The highest incidence of pediatric epilepsy is in the first year of life. Most infantile epilepsies have presumed genetic etiologies and timely precision genetic diagnosis is increasingly possible. However, treatment remains largely symptomatic and outcomes poor due to a gap from precision diagnoses to precision therapies. Antisense oligonucleotide therapies are a precision therapy approach th...

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Literature Corpus work: 1553b2c9-b377-5a76-81e5-c5fd9b23e8cc
DOI: 10.64898/2025.12.02.25341084

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