Article

M6A demethylase FTO-stabilized exosomal circBRCA1 alleviates oxidative stress-induced granulosa cell damage via the miR-642a-5p/FOXO1 axis

2024-01-30

Abstract excerpt

<h4>Background: </h4> Premature ovarian insufficiency (POI) is an important cause of female infertility and seriously impacts the physical and psychological health of patients. Human umbilical cord mesenchymal stem cell-derived exosomes (HucMSCs-Exs, H-Exs) have exhibited protective effects on ovarian function with unclear mechanisms. <h4>Methods: </h4>: A comprehensive analysis of the Gene Expression Omnibus (GEO...

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Literature Corpus work: 148b8341-ddc1-56e0-8370-c093fcdb50c0
DOI: 10.21203/rs.3.rs-3894773/v1

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