Article

Temporal Fluctuations of Gut Microbiota and Bile Acid Metabolism in Critically Ill Children

2021-06-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Critical illness frequently requires the use of broad-spectrum antimicrobials to treat life-threatening infection. The resulting impact on microbiome diversity is profound, influencing gastrointestinal fermentation endpoints, host immune response and metabolic activity including the conversion of primary bile acids to secondary bile acids. We previously observed...

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Literature Corpus work: 148231e8-0815-530c-846d-ce1bdf240b5e
DOI: 10.21203/rs.3.rs-647124/v1

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