Article
A scalable cell-free manufacturing platform for two-step bioproduction of immunogenic conjugate vaccines
2025-08-06
Abstract excerpt
Rapid and decentralized vaccine production is essential to ensure global preparedness against emerging and re-emerging infectious diseases. Cell-free gene expression systems, which can be freeze-dried for long-term storage and re-activated for point-of-use synthesis, offer a promising solution to address this need. However, scalable cell-free production of conjugate vaccines-highly effective tools against bacteria...
Topics
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- Bacteriophages and microbial interactions
- Escherichia coli research studies
- Monoclonal and Polyclonal Antibodies Research
- Probiotics and Fermented Foods
- Protein purification and stability
- Transgenic Plants and Applications
- Viral gastroenteritis research and epidemiology
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- 147a2be1-5c33-5371-b718-ff732e31eaa8
- DOI
- 10.1101/2025.08.05.668792
