Article

Immunohistochemical Characterization of Cell of Origin in Diffuse Large B-cell Lymphoma and its Correlation with the Double Expressor Phenotype: A Retrospective Study in a Tertiary Cancer Care Centre

2021-08-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background – </bold>Diffuse Large B Cell Lymphoma (DLBCL) is the most common type of Non- Hodgkin Lymphoma (NHL) and is categorized into the Germinal Centre B-cell (GCB) and Activated B-cell (ABC/ Non-GCB) subtypes as per the Cell-of-origin (COO) model with the help of Gene Expression Profiling/ Immunohistochemistry. The non -GCB subtype has been found to correlate with the Double...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1459b270-1b24-5827-90f9-2fef44e2ce41
DOI: 10.21203/rs.3.rs-763051/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Immunohistochemical Characterization of Cell of Origin in Diffuse Large B-cell Lymphoma and its Correlation with the Double Expressor Phenotype: A Retrospective Study in a Tertiary Cancer Care CentreDOI 10.21203/rs.3.rs-763051/v1Read

Are We Ready To Stratify Treatment for Diffuse Large B-Cell Lymphoma Using Molecular Hallmarks?Semantic proximity Read

Primary Bone Diffuse Large B-cell Lymphoma (PB-DLBCL) – a distinct extranodal lymphoma of germinal center origin, with an EZB-like mutational profile and good prognosisSemantic proximity Read

Diagnosis of 'double hit' diffuse large B-cell lymphoma and B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and Burkitt lymphoma: when and how, FISH versus IHC.Semantic proximity Read

Double hit lymphoma: from biology to therapeutic implications.Semantic proximity Read

Cell-of-Origin Subtyping of Diffuse Large B-Cell Lymphoma by Using a qPCR-based Gene Expression Assay on Formalin-Fixed Paraffin-Embedded TissuesSemantic proximity Read

Clinical features and immunophenotypes of double-hit diffuse large B-cell lymphomaSemantic proximity Read

Molecular background delineates outcome of double protein expressor diffuse large B-cell lymphomaSemantic proximity Read

Diffuse large B-cell lymphoma.Semantic proximity Read

Primary bone diffuse large B-cell lymphoma (PB-DLBCL): a distinct extranodal lymphoma of germinal centre origin, with a common EZB-like mutational profile and good prognosis.Semantic proximity Read

[Diffuse large B-cell lymphoma: therapeutic development based on clinical and biological heterogeneity].Semantic proximity Read

Cell-of-Origin in Diffuse Large B-Cell Lymphoma: Are the Assays Ready for the Clinic?Semantic proximity Read

The prognostic significance of MYC/BCL2 double expression in DLBCL in the genetic classification era.Semantic proximity Read