Article

Aetiological factors in the pathogenesis of male genital lichen sclerosus, penile precancer and penile cancer

2017-01-01

Abstract excerpt

Male genital lichen sclerosus (MGLSc) results in sexual and urological dysfunction and predisposes to penile intraepithelial neoplasia (PeIN) and squamous cell carcinoma of the penis (PSCC). The pathogenesis of MGLSc is controversial. Evidence has accumulated that it is due to chronic, occluded exposure to urine caused by post-micturition microincontinence. Infection with hepatitis C (HCV) or human papillomavirus...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1426aa5e-2ffe-5fdb-aa1a-163e6258da5c
DOI: 10.25560/45003

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Aetiological factors in the pathogenesis of male genital lichen sclerosus, penile precancer and penile cancerDOI 10.25560/45003Read

Immunogenetics and human papillomavirus (HPV) in male genital lichen sclerosus (MGLSc).Semantic proximity Read

A Direct Comparative Analysis of HPV DNA with Single-Molecule RNA and p16INK4a Protein Expression in Lichen Sclerosus: Implications for Diagnostics and PathogenesisSemantic proximity Read

Lichen sclerosus and the risk of malignant progression: a case series of 159 patients.Semantic proximity Read

Human papillomavirus, lichen sclerosus and penile cancer: a study in Belgium.Semantic proximity Read

Multi-omics analysis reveals the host-microbe interactions on the dysbiosis of tissue microbiota in male genital lichen sclerosus- induced urethral stricturesSemantic proximity Read

Molecular Subtypes of Balanopreputial and Urethral Male Genital Lichen Sclerosus: Distinct Transcriptomic and Clinicopathological ProfilesSemantic proximity Read

Gene expression profiling in male genital lichen sclerosusSemantic proximity Read

Two major pathways of penile carcinogenesis: HPV-induced penile cancers overexpress p16ink4a, HPV-negative cancers associated with dermatoses express p53, but lack p16ink4a overexpression.Semantic proximity Read

Unique genital microbiota in male lichen sclerosus urethral stricture associated with urine exposureSemantic proximity Read

Multi-omics analysis reveals the host-microbe interactions on the dysbiosis of tissue microbiota in male genital lichen sclerosus-induced urethral stricturesSemantic proximity Read

Synchronous genitourinary lichen sclerosus signals a distinct urinary microbiome profile in men with urethral stricture diseaseSemantic proximity Read

The vulvar microbiome in lichen sclerosus and high-grade intraepithelial lesionsSemantic proximity Read