Article

(Hydroxy-) Chloroquine, G6PD deficiency, and sex differences in mortality during the COVID-19 pandemic: An ecological study in Peru

2025-12-29

Abstract excerpt

<title>Abstract</title> <p>Background Peru implemented a nationwide chloroquine/hydroxychloroquine (CQ/HCQ) treatment policy during the early phase of the COVID-19 pandemic. Whether these drugs trigger hemolytic crises in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PDd), a genetic condition primarily affecting men, with a relatively high prevalence in certain regions, is a matter of debate....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 13bf78e2-2355-52c6-8008-4cefd78fe221
DOI: 10.21203/rs.3.rs-8030418/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

(Hydroxy-) Chloroquine, G6PD deficiency, and sex differences in mortality during the COVID-19 pandemic: An ecological study in PeruDOI 10.21203/rs.3.rs-8030418/v1Read

Is glucose-6-phosphate dehydrogenase deficiency associated with COVID-19 infection, severity, and death? A cohort study from the Brazilian AmazonSemantic proximity Read

Hydroxychloroquine and mortality risk of patients with COVID-19: a systematic review and meta-analysis of human comparative studiesSemantic proximity Read

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19: an international collaborative meta-analysis of randomized trialsSemantic proximity Read

Paucity and disparity of publicly available sex-disaggregated data for the COVID-19 epidemic hamper evidence-based decision-makingSemantic proximity Read

Low dose hydroxychloroquine is associated with lower mortality in COVID-19: a meta-analysis of 26 studies and 44,521 patientsSemantic proximity Read

Disentangling the association of hydroxychloroquine treatment with mortality in Covid-19 hospitalized patients through Hierarchical ClusteringSemantic proximity Read

Hydroxychloroquine/Chloroquine in COVID-19 With Focus on Hospitalized Patients – A Systematic ReviewSemantic proximity Read

Determinants of hydroxychloroquine-mediated hemolytic anemia in G6PD-deficient COVID-19 patientsSemantic proximity Read

Sharp Reductions in COVID-19 Case Fatalities and Excess Deaths in Peru in Close Time Conjunction, State-By-State, with Ivermectin TreatmentsSemantic proximity Read

Pooled evidence precision of clinical trials on hydroxychloroquine for Covid-19 treatment was stabilized eight months after the outbreakSemantic proximity Read

Mass Intake of Hydroxychloroquine or Chloroquine in the Present Context of the COVID-19 Outbreak: Possible Consequences in Endemic Malaria SettingsSemantic proximity Read

Changes in malaria patterns in Brazil over 28 years (1990-2017): results from the Global Burden of Disease Study 2017Semantic proximity Read