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Designing to Implement Genomics Informed ASCVD Risk Assessment: Patient and Clinician Perspectives about Identifying and Managing the Underlying Causes of Severe Hypercholesterolemia

2026-08-12

Abstract excerpt

<h4>Introduction</h4> Severe hypercholesterolemia has four primary causes: monogenic familial hypercholesterolemia (FH), polygenic hypercholesterolemia (PRS), severely elevated Lp(a) concentration, and hypercholesterolemia due to environmental/lifestyle/behavioral factors (i.e., no known genetic etiology). Here, we explore patient and clinician perspectives about the identification and management of each of these...

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Literature Corpus work: 13014e9d-e698-5516-ab67-f3c1691760b9
DOI: 10.64898/2026.08.10.26360146

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