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Serial ‘deep-sampling’ PCR of fragmented DNA reveals the wide range of <i>Trypanosoma cruzi</i> burden among chronically infected hosts and allows accurate monitoring of parasite load following treatment

2024-06-10

Abstract excerpt

Infection with the protozoan parasite Trypanosoma cruzi is generally well-controlled by host immune responses, but appears to be rarely eliminated. The resulting persistent, low-level infection results in cumulative tissue damage with the greatest impact generally in the heart in the form of chagasic cardiomyopathy. The relative success in immune control of T. cruzi infection usually averts acute phase death but...

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Literature Corpus work
12af3ea2-cbb9-523b-af2f-dff399acf76a
DOI
10.1101/2024.06.10.598182
Open publication

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Serial ‘deep-sampling’ PCR of fragmented DNA reveals the wide range of <i>Trypanosoma cruzi</i> burden among chronically infected hosts and allows accurate monitoring of parasite load following treatmentDOI 10.1101/2024.06.10.598182
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