Article

Unambiguous signatures of malignancies extracted from images of growing cells

2026-01-13

Abstract excerpt

As malignant transformation arises from dysregulated cellular programming with characteristic morphological changes, we hypothesized that cancer cells exhibit a unique morphological signature detectable in microscopy images of cells in vitro and in situ across modalities. To test this, we developed CellSign , an AI-based framework to generate Cell Dynamics Fingerprints, which (a) reconstruct morphological progres...

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Literature Corpus work: 12948c5c-b92d-5b9c-8f1c-e39415d65d17
DOI: 10.64898/2026.01.10.26343803

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