Article

Exploiting Molecular Basis of Age and Gender Differences in Outcomes of SARS-CoV-2 Infections

2021-05-25

Abstract excerpt

<h4>Motivation</h4> Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It has been observed that lethality seems to be related to the age of patients. Moreover, it has been demonstrated that ageing causes some modifications at a molecular level. <h4>Objective</h4> The study aims to shed out light on a possibl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 127d452a-fe45-53cc-93ba-613757dfa800
DOI: 10.1101/2021.05.23.21257669

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exploiting Molecular Basis of Age and Gender Differences in Outcomes of SARS-CoV-2 InfectionsDOI 10.1101/2021.05.23.21257669Read

Intersection between ageing-related Genes and SARS-CoV-2 Interactome: Is it higher than expected?Semantic proximity Read

COVID-19 is an emergent disease of agingSemantic proximity Read

COVID-19 and Crosstalk With the Hallmarks of AgingSemantic proximity Read

Cumulative effect of aging and SARS-CoV2 infection on poor prognosis in the elderly: Insights from transcriptomic analysis of lung and bloodSemantic proximity Read

Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 SurvivorsSemantic proximity Read

The Molecular Basis of Gender Variations in Mortality Rates Associated with the Novel Coronavirus (COVID-19) OutbreakSemantic proximity Read

The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2Semantic proximity Read

Genetic and epigenetic factors associated with increased severity of Covid‐19Semantic proximity Read

Specific immune-regulatory transcriptional signatures reveal sex and age differences in SARS-CoV-2 infected patientsSemantic proximity Read

Identification of Age-Related Characteristic Genes Involved in Severe COVID-19 Infection Among Elderly Patients using Machine Learning and Immune Cell Infiltration AnalysisSemantic proximity Read

Premature aging effects on COVID-19 pathogenesis: new insights from mouse modelsSemantic proximity Read

Why Does COVID-19 Disproportionately Affect the Elderly?Semantic proximity Read