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Ceftazidime–Avibactam Resistance in <i>Escherichia coli</i> Primarily Mediated by <i>bla</i> <sub>NDM-5</sub> with Emergent Ceftazidime–Avibactam/Aztreonam Resistance Linked to <i>bla</i> <sub>CMY-42</sub> Variants

2025-12-07

Abstract excerpt

<h4>ABSTRACT</h4> Ceftazidime–avibactam (CZA) has revolutionized care for carbapenem-resistant Enterobacterales infections, yet increasing New Delhi metallo-β-lactamase (NDM) prevalence has driven use of CZA plus aztreonam (CZA/ATM). We performed a comprehensive analysis of CZA-resistant Escherichia coli (CZA-R- Ec ) at a tertiary cancer center (2017–2024) by integrating clinical data, comparative genomics, and...

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Literature Corpus work
1233dc1f-8f12-5fa1-a62a-6e2510a8049a
DOI
10.64898/2025.12.05.25341718
Open publication

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Ceftazidime–Avibactam Resistance in <i>Escherichia coli</i> Primarily Mediated by <i>bla</i> <sub>NDM-5</sub> with Emergent Ceftazidime–Avibactam/Aztreonam Resistance Linked to <i>bla</i> <sub>CMY-42</sub> VariantsDOI 10.64898/2025.12.05.25341718
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