Article

Genetic, demographic and clinical variables act synergistically to impact neurodevelopmental outcomes in children with single ventricle heart disease

2022-10-04

Abstract excerpt

<h4>ABSTRACT</h4> Recent large-scale sequencing efforts have shed light on the genetic contribution to the etiology of congenital heart defects (CHD); however, the relative impact of genetics on clinical outcomes remains less understood. Outcomes analyses using genetic data are complicated by the intrinsic severity of the CHD lesion and by interactions with conditionally dependent clinical variables. Here we apply...

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Literature Corpus work: 11f5e48f-160b-58d9-b422-0e215043e80f
DOI: 10.1101/2022.10.01.22280594

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