Article

Gestational insulin resistance is mediated by the gut microbiome-indoleamine 2,3-dioxygenase axis

2021-07-22

Abstract excerpt

<h4>Background and aims</h4> Normal gestation involves reprogramming of maternal gut microbiome (GM) that may contribute to maternal metabolic changes by unclear mechanisms. This study aimed to understand the mechanistic underpinnings of GM – maternal metabolism interaction. <h4>Methods</h4> The GM and plasma metabolome of CD1, NIH-Swiss and C57BL/6J mice were analyzed using 16S rRNA sequencing and untargeted LC...

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Literature Corpus work: 11f45790-2b6c-5455-bfd4-88531dfe6536
DOI: 10.1101/2021.07.21.453234

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