Article
Offspring metabolic programming via the maternal diet increases susceptibility to metabolic dysregulation
26 Jun 2025
Abstract excerpt
BACKGROUND: Maternal nutrition during critical developmental windows is crucial for offspring metabolic programming. Methionine, an essential amino acid, is crucial in pancreatic differentiation. However, the impact of a maternal methionine-deficiency (MD) diet on offspring during the critical stage of embryonic pancreatic differentiation remains unclear. METHODS: We used an in vitro human induced pluripotent...
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