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<i>Candida albicans</i> infiltrates colon and rectal cancers causing therapeutic resistance and decreased survival

2025-09-21

Abstract excerpt

The microbiome is increasingly recognized as a modifier of cancer progression and therapy response, yet the role of intratumoral fungi remains poorly defined. Here, we identify Candida albicans colonization within human colorectal tumors as a predictor of reduced survival and impaired radiation response. Leveraging the Oncology Research Information Exchange Network (ORIEN) cohort, we show that high intratumoral...

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Identifiers and source

Literature Corpus work
11b37e1a-5cd1-5e88-b1e0-2a2e8a75f150
DOI
10.1101/2025.09.19.677366
Open publication

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<i>Candida albicans</i> infiltrates colon and rectal cancers causing therapeutic resistance and decreased survivalDOI 10.1101/2025.09.19.677366
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