Article

Network-based protein-protein interaction prediction method maps perturbations of cancer interactome

2020-07-02

Abstract excerpt

The perturbations of protein-protein interactions (PPIs) were found to be the main cause of cancer. Previous gene relationship prediction methods which were trained with non-disease gene interaction data were not compatible to map the PPI network in cancer. Therefore, we established a novel cancer specific PPI prediction method dubbed NECARE, which was based on relational graph convolutional network (R-GCN) with k...

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Literature Corpus work: 11397e93-d88e-5a70-acac-7de809a919b3
DOI: 10.1101/2020.07.01.181776

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