Article

Determinants of Blood Group Antigen Expression and Prediction of Phenotypes by Machine Learning

2026-07-07

Abstract excerpt

Blood group antigens, defined by epitopes on the erythrocyte surface, are central to transfusion safety and maternal-fetal compatibility. While the genetic basis of many clinically relevant blood group antigens is well established, which structural and biophysical parameters determine whether a single-nucleotide variant gives rise to an antigenic phenotype remains unclear. Here, we integrate structural, biophysica...

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Literature Corpus work: 100ca32c-42a5-5fde-acca-8d3201620ec2
DOI: 10.64898/2026.07.01.735824

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