Article

Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling

2023-04-12

Abstract excerpt

<h4>ABSTRACT</h4> Defects in blood development frequently occur among syndromic congenital anomalies. Thrombocytopenia-Absent Radius (TAR) syndrome is a rare congenital condition with reduced platelets (hypomegakaryocytic thrombocytopenia) and forelimb anomalies, concurrent with more variable heart and kidney defects. TAR syndrome associates with hypomorphic gene function for RBM8A/Y14 that encodes a component o...

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Literature Corpus work: 0f49502d-daeb-5ead-a65b-2fb88173dd48
DOI: 10.1101/2023.04.12.536513

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