Article

Regulation of Renal and Extrarenal Calcitriol Synthesis and Its Clinical Implications

2025-05-05

Abstract excerpt

There is evidence that calcitriol is the only biologically active vitamin D metabolite. This review summarizes data on the regulation of renal and extrarenal synthesis of calcitriol by nutritional, physiologic, mechanical, genetic, and disease-related factors. Relatively low circulating calcitriol due to low substrate availability, i.e. low circulating 25-hydroxyvitamin D, has been reported in nutritional rickets,...

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Literature Corpus work: 0efc8c2c-fb40-5478-8387-861d87c2dfef
DOI: 10.20944/preprints202505.0111.v1

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