Article
Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment.
Endocrine reviews - 1 Oct 2016
Tebben Peter J, Singh Ravinder J, Kumar Rajiv
Abstract excerpt
Hypercalcemia occurs in up to 4% of the population in association with malignancy, primary hyperparathyroidism, ingestion of excessive calcium and/or vitamin D, ectopic production of 1,25-dihydroxyvitamin D [1,25(OH)2D], and impaired degradation of 1,25(OH)2D. The ingestion of excessive amounts of vitamin D3 (or vitamin D2) results in hypercalcemia and hypercalciuria due to the formation of supraphysiological...
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