Article

The relationship between mucosal microbiota, colitis and systemic inflammation in Chronic Granulomatous Disorder

2021-07-06

Abstract excerpt

<h4>Background</h4> Chronic granulomatous disorder (CGD) is a primary immunodeficiency which is frequently complicated by an inflammatory colitis and is associated with systemic inflammation. <h4>Objective</h4> To investigate the role of the microbiome in the pathogenesis of colitis and systemic inflammation. <h4>Methods</h4> We performed 16S rDNA sequencing on mucosal biopsy samples from each segment of 10 CGD...

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Literature Corpus work: 0ef8db6e-d866-5c8b-b28d-834126d1d80b
DOI: 10.1101/2021.07.05.451147

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