Aging Is Triggered by Exercise and Suppressed by a Diet Containing Bean Sprouts in a Senescence-Accelerated Prone 1 (SAMP1) Mouse Model of Aging

Abstract excerpt

1) Background: Coumestrol is a bioactive compound that inhibits HASPIN activity and prevents tau and H3 phosphorylation. Oral ingestion of CBSs increases blood testosterone levels, which decline with age causing late-onset hypogonadism. Oral ingestion of coumestrol-rich bean sprouts (CBSs) has been shown to suppress the onset of Alzheimer’s disease in 5xFAD mice and the onset of colon cancer in APCmin/+ mice. 2) M...

Topics

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• Adipose Tissue and Metabolism
• Biochemical effects in animals
• Circadian rhythm and melatonin
• Genomics, phytochemicals, and oxidative stress
• Mitochondrial Function and Pathology
• Phytochemicals and Antioxidant Activities
• Phytoestrogen effects and research
• Sirtuins and Resveratrol in Medicine

Identifiers and source

Literature Corpus work

0de7b18f-3639-5205-a171-4688c92d6336

DOI

10.20944/preprints202605.1338.v1