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Overexpression of oncogenic spliced-AGR2vH potentiates cholangiocarcinoma cell tumorigenicity with proteomic alterations

2021-05-17

Abstract excerpt

<title>Abstract</title> <p>Upregulated expression of Anterior gradient 2 (AGR2) has been observed in cells, highly metastatic mouse models, nras-mutant zebrafish and cholangiocarcinoma <bold>(</bold>CCA) specimens derived from patients. Our previous study reported that AGR2 splicing into AGR2vH can promote CCA cell metastasis and survivability. This present study aimed to investigate the molecular mechanisms unde...

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Literature Corpus work
0d84fe3e-3bd6-5e72-966f-5ff1b4cf9257
DOI
10.21203/rs.3.rs-512824/v1
Open publication

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Overexpression of oncogenic spliced-AGR2vH potentiates cholangiocarcinoma cell tumorigenicity with proteomic alterationsDOI 10.21203/rs.3.rs-512824/v1
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