Article
Anterior gradient 2 is correlated with EGFR mutation in lung adenocarcinoma tissues.
The International journal of biological markers - 26 May 2015
Narumi Sodai, Miki Yasuhiro, Hata Shuko, Ebina Masahito, Saito Mikiyoshi, Mori Kazushige, Kobayashi Makoto, Suzuki Takashi, Iwabuchi Erina, Sato Ikuro, Maemondo Makoto, Endo Chiaki, Inoue Akira, Kondo Takashi, Yamada-Okabe Hisafumi, Ichinose Masakazu, Sasano Hironobu
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) has demonstrated a promising therapeutic response in lung adenocarcinoma patients with EGFR gene mutations. However, the predictive factors for this therapy have not been established, except for the EGFR gene mutation status of carcinoma cells. METHODS: We first performed microarray analysis in EGFR-TKI-sensitive lung...
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