Article

Efficient Identification of Short Tandem Repeats via Context-Aware Motif Discovery and Ultra-Fast Sequence Alignment

2025-11-28

Abstract excerpt

Tandem repeats (TRs) are highly polymorphic genomic elements, associated with diverse molecular traits and implicated in numerous human diseases. However, large-scale analysis of TRs has been limited by computational challenges, including motif recognition, detection in complex regions, and excessive computational cost. Here we present FastSTR, a computationally efficient tool for precise detection and characteriz...

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Literature Corpus work: 0cc77af4-70d0-596c-a881-0d40cf3e7fa6
DOI: 10.1101/2025.11.25.690584

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