Article
A NEW PERSPECTIVE ON ISOTRETINOIN IN PREGNANCY: PREGNANCY OUTCOMES, EVALUATION OF COMPLEX PHENOTYPES, AND IMPORTANCE OF TERATOLOGICAL COUNSELLING
2023-06-05
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Background</h4> Teratogens are responsible for 5% of all known causes of congenital anomalies. Isotretinoin, a retinoic acid–derived agent, leads to congenital anomalies in 21-52% of cases when exposure occurs during pregnancy according to studies conducted before 2006. However, rates of congenital anomalies were much lower in later studies. <h4>Objectives</h4> To investigate the rates of con...
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Identifiers and source
- Literature Corpus work
- 0c16f44a-1a1d-5144-8fb6-b3c5a6813073
- DOI
- 10.1101/2023.06.02.23290862
