Article

A novel computational methodology for GWAS multi-locus analysis based on graph theory and machine learning

2021-10-26

Abstract excerpt

<h4>Background</h4> Current form of genome-wide association studies (GWAS) is inadequate to accurately explain the genetics of complex traits due to the lack of sufficient statistical power. It explores each variant individually, but current studies show that multiple variants with varying effect sizes actually act in a concerted way to develop a complex disease. To address this issue, we have developed an algorit...

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Literature Corpus work: 0be86a89-55a0-55dd-8066-dcc0534b3d0e
DOI: 10.1101/2021.10.22.21265388

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