Back to search

Article

Universal nature of drug treatment responses in drug-tissue-wide model-animal experiments using tensor decomposition-based unsupervised feature extraction

2020-03-09

Abstract excerpt

<h4>ABSTRACT</h4> Gene expression profiles of tissues treated with drugs have recently been used to infer clinical outcomes. Although this method is often successful from the application point of view, gene expression altered by drugs is rarely analyzed in detail, because of the extremely large number of genes involved. Here, we applied tensor decomposition (TD)-based unsupervised feature extraction (FE) to the g...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0b7ab2d4-02db-59c4-9afc-dcd7295e122c
DOI
10.1101/2020.03.08.982405
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Universal nature of drug treatment responses in drug-tissue-wide model-animal experiments using tensor decomposition-based unsupervised feature extractionDOI 10.1101/2020.03.08.982405
Identification of Candidate Drugs for Heart Failure using Tensor Decomposition-Based Unsupervised Feature Extraction Applied to Integrated Analysis of Gene Expression between Heart Failure and DrugMatrix DatasetsSemantic proximity
Neurological disorder drug discovery from gene expression with tensor decompositionSemantic proximity
Novel Method for Detection of Genes With Altered Expression Caused by Coronavirus Infection and Screening of Candidate Drugs for SARS-CoV-2Semantic proximity
Tensor decomposition-Based Unsupervised Feature Extraction Applied to Single-Cell Gene Expression AnalysisSemantic proximity
Novel artificial intelligence-based identification of drug-gene-disease interaction using protein-protein interactionSemantic proximity
A New Advanced <em>In silico</em> Drug Discovery Method for Novel Coronavirus (SARS-CoV-2) with Tensor Decomposition-based Unsupervised Feature ExtractionSemantic proximity
Tensor decomposition- and principal component analysis-based unsupervised feature extraction to select more reasonable differentially expressed genes: Optimization of standard deviation versus state-of-art methodsSemantic proximity
TDbasedUFE and TDbasedUFEadv: bioconductor packages to perform tensor decomposition based unsupervised feature extractionSemantic proximity
PharmOmics: A Species- and Tissue-specific Drug Signature Database and Online Tool for Drug RepurposingSemantic proximity
Integrated Analysis of Tissue-specific Gene Expression in Diabetes by Tensor Decomposition Can Identify Possible Associated DiseasesSemantic proximity
A tensor decomposition-based integrated analysis applicable to multiple gene expression profiles without sample matchingSemantic proximity
A New Approach to Drug Repurposing with Two-Stage Prediction, Machine Learning, and Unsupervised Clustering of Gene ExpressionSemantic proximity
Select a neighboring publication to make it the new centre.