Article
An Integrated Comparative Genomics, Subtractive Proteomics and Immunoinformatics Framework for the Rational Design of a Pan- <i>Salmonella</i> Multi-Epitope Vaccine
2023-09-23
Abstract excerpt
Salmonella infections are a global public health issue due to the high cost of illness surveillance, prevention, and treatment. In this study, we explored the core proteome in Salmonella to design a multi-epitope vaccine through Subtractive Proteomics and immunoinformatics approaches. A total of 2395 core proteins presents in 30 different strains of Salmonella (reference strain-NZ CP014051) were curated. Utilizi...
Topics
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- Bacteriophages and microbial interactions
- Biochemical and Structural Characterization
- Clostridium difficile and Clostridium perfringens research
- Hepatitis B Virus Studies
- Immunotherapy and Immune Responses
- Monoclonal and Polyclonal Antibodies Research
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
Identifiers and source
- Literature Corpus work
- 0b5be8ce-3911-542d-a2ed-62ea8a57f73c
- DOI
- 10.1101/2023.09.21.558749
