Article

Therapeutic angiogenesis with intramuscular SeV-hFGF2/dF for the treatment of peripheral arterial disease: a phase I clinical trial

2023-03-13

Abstract excerpt

This paper reports a phase I dose-escalation clinical trial for the treatment of peripheral arterial disease (PAD) with BF30, a recombinant Sendai virus vector carrying the human native fibroblast growth factor 2 (hFGF2) gene. Our goal was to evaluate the safety and tolerability of BF30 at varying doses while assessing its preliminary therapeutic effect. Twelve male patients with PAD unsuitable for revascularizati...

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Literature Corpus work: 0b108c19-31a4-5283-8e80-a44bcd976ca3
DOI: 10.21203/rs.3.rs-2653535/v1

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