Article

A spinal origin for the obligate flexor synergy in the non-human primate: Implications for control of reaching

2025-07-30

Abstract excerpt

Stroke survivors frequently develop the flexor synergy, an obligate co-contraction of shoulder abductors and elbow flexors; the neural substrate has proven elusive. Here we trained healthy monkeys to generate isometric elbow and shoulder torques to move an on-screen cursor, and recorded neuron firing from motor cortical areas and the reticular formation. In all regions we found cells correlated with activity aroun...

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Literature Corpus work: 0b00876d-2434-5c5c-8335-4a70cb8ef2e1
DOI: 10.1101/2025.07.28.666086

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