Article

Lytic anti- <i>Staphylococcus aureus</i> phage M963 resensitizes its host to methicillin by a <i>tarS</i> -dependent mechanism

2025-12-19

Abstract excerpt

Bacteriophage M963 targeting a clinical strain of methicillin-resistant Staphylococcus aureus (MRSA) was isolated from wastewater. Purification was optimized and the phage was subsequently characterized as a lytic, dsDNA phage within the family Roundtreeviridae and genus Rosenblumvirus . Host range testing against a small library of S. aureus isolates from patients with bacteremia and periprosthetic joint infe...

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Literature Corpus work: 0ab1bbb6-780a-5869-b951-d9a97c2b5dfd
DOI: 10.64898/2025.12.19.695355

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