Article

A comprehensive analysis of dominant and recessive parkinsonism genes in REM sleep behavior disorder

2020-03-20

Abstract excerpt

<h4>Objective</h4> To examine the role of autosomal dominant (AD) and recessive (AR) Parkinsonism genes in the risk of isolated rapid-eye-movement (REM) sleep behavior disorder (iRBD). <h4>Methods</h4> Ten genes implicated in AD and AR Parkinsonism were fully sequenced using targeted next-generation sequencing in 1,039 iRBD patients and 1,852 controls of European ancestry. These include the AR genes PRKN, DJ-1 (PA...

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Literature Corpus work: 0ab1b601-c2d6-5a63-accc-4962ccfd941d
DOI: 10.1101/2020.03.17.20032664

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