Article

In-silico Identification of Novel Drug Target for Osteoarthritisinhuman using System Network Biology Approaches

2020-06-25

Abstract excerpt

Osteoarthritis (OA) is the most common form of joint disability in the world affecting a large number of persons s yet the mechanisms responsible for the disease is not well n understood. And therefore there is a lack of disease-modifying treatment options. It has several risk factors from systemic (e.g. age, sex, genetics, obesity) to biochemical factors (e.g. joint injury, muscle weakness, sport). The preva...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0a930307-bc00-5984-8416-0e1961169913
DOI: 10.26434/chemrxiv.12548030.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

In-silico Identification of Novel Drug Target for Osteoarthritisinhuman using System Network Biology ApproachesDOI 10.26434/chemrxiv.12548030.v1Read

Potential candidate biomarkers associated with osteoarthritis: Evidence from a comprehensive network and pathway analysisSemantic proximity Read

Multi-tissue network analysis for drug prioritization in knee osteoarthritisSemantic proximity Read

Identification and Validation of Pivotal Genes in Osteoarthritis Combined with WGCNA AnalysisSemantic proximity Read

Identification of key regulators responsible for dysregulated networks in osteoarthritis by large-scale expression analysisSemantic proximity Read

The Analysis of The Application and Mechanism of Traditional Chinese Medicine in Osteoarthritis Based on Data Mining and Network PharmacologySemantic proximity Read

Analyzing network pharmacology and molecular docking to clarify Duhuo Jisheng decoction potential mechanism of osteoarthritis mitigationSemantic proximity Read

Study of Osteoarthritis‐Related Hub Genes Based on Bioinformatics AnalysisSemantic proximity Read

Integrated Network Pharmacology Reveals the Mechanism of Action of Xianlinggubao Prescription for inflammation in OsteoarthritisSemantic proximity Read

Identification of the Biomarkers and Pathological Process of Osteoarthritis: Weighted Gene Co-expression Network AnalysisSemantic proximity Read

Identification of gene expression profiles and key genes in subchondral bone of osteoarthritis using weighted gene coexpression network analysis.Semantic proximity Read

Identification of key regulators responsible for dysregulated networks in osteoarthritis by large-scale expression analysisSemantic proximity Read

Screening and validation of key genes associated with osteoarthritisSemantic proximity Read