Article
Lipoprotein Apheresis and Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors in Patients With Heterozygous Familial Hypercholesterolemia: A One Center Study.
Journal of cardiovascular pharmacology and therapeutics - 1 Jan 2021
Kolovou Vana, Katsiki Niki, Makrygiannis Stamatis, Mavrogieni Sophie, Karampetsou Nikoletta, Manolis Athanasios, Melidonis Andreas, Mikhailidis Dimitri P, Kolovou Genovefa D
Abstract excerpt
AIM: We evaluated the lipid-lowering (LL) effect of proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) in patients with heterozygous familial hypercholesterolemia (HeFH) treated with LL-drugs and lipoprotein apheresis (LA). PATIENTS AND METHODS: The PCSK9i treatment (evolocumab 420 mg/4 weeks, alirocumab 150 mg/2 weeks, or alirocumab 75 mg/2 weeks: 9, 6, and 2 patients, respectively) was initiated...
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