Site of breast cancer metastasis is independent of single nutrient levels

Abstract excerpt

Cancer metastasis is a major contributor to patient morbidity and mortality 1 , yet the factors that determine the organs where cancers can metastasize are incompletely understood. In this study, we quantify the absolute levels of over 100 nutrients available across multiple tissues in mice and investigate how this relates to the ability of breast cancer cells to grow in different organs. We engineered breast can...

Topics

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• Cell Proliferation
• Disease Progression
• Metabolic Networks and Pathways
• Mutation
• Neoplasms
• Nutrients
• Nutritional Requirements
• Tumor Microenvironment

Identifiers and source

Literature Corpus work

09bfba25-c455-5c96-9369-536f0fd56523

DOI

10.1101/2024.10.24.616714