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Identification of a Novel Nonsense Homozygous Mutation of LINS1 Gene in Two Sisters With Moderate Intellectual Disability, Schizophrenia, and Anxiety Disorders and Review of the Literature

2020-09-16

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<title>Abstract</title> <p><bold>Background: </bold>The human<italic> LINS1 </italic>gene is located at 15q26.3 and encodes the lines homolog 1 protein that contains the <italic>Drosophila lines</italic> homologous domain. Mutations in the <italic>LINS1</italic> gene have been reported to cause a rare recessive form of intellectual disability. A total of seven mutations in six studies have been reported in the li...

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Literature Corpus work: 096f46c4-46d6-5067-97de-d7878899d264
DOI: 10.21203/rs.3.rs-76249/v1

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Identification of a Novel Nonsense Homozygous Mutation of LINS1&nbsp;Gene in Two Sisters With Moderate Intellectual Disability, Schizophrenia, and Anxiety Disorders and Review of the Literature

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Identification of a Novel Nonsense Homozygous Mutation of LINS1 Gene in Two Sisters With Moderate Intellectual Disability, Schizophrenia, and Anxiety Disorders and Review of the Literature