Article
The high expression of elastases, observed in apelin deficient mice, could contribute to premature wear of elastic fibers and vascular stiffness.
2021-02-11
Abstract excerpt
Vascular stiffness is often the main cause of arterial hypertension and its complications including atherosclerosis, observed during obesity. However, the mechanisms leading to this rigidity or the preventing factors are misknown. We hypothesized that apelin, known for its beneficial effects on lipid, inflammatory, and vascular metabolism, could be a protective factor against vascular stiffness. We used mice defic...
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Identifiers and source
- Literature Corpus work
- 093e06af-cfff-5dc3-b93d-2bd55a1ebfdb
- DOI
- 10.21203/rs.3.rs-153958/v1