Article

S100PBP is regulated by mutated KRAS and plays a tumour suppressor role in pancreatic cancer

2023-04-18

Abstract excerpt

<title>Abstract</title> <p>We have previously shown that expression of S100PBP, an S100P binding partner, gradually decreases during progression of pancreatic ductal adenocarcinomas (PDAC). Here, we show that loss of S100PBP leads to oncogenic transformation of pancreatic cells; after deregulation of <italic>S100PBP</italic> expression, both <italic>in silico</italic> and <italic>in vitro</italic> analyses highli...

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Identifiers and source

Literature Corpus work: 0914c94b-641a-5a5e-8e98-a2d9e2d816e0
DOI: 10.21203/rs.3.rs-2731268/v1

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